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American Society of Microbiology ABMM Sample Questions:

1. A patient develops a localized skin infection after being bitten by a tick. The infection is characterized by a slowly expanding erythematous rash with central clearing (erythema migrans). The MOST likely causative agent is:

A) Borrelia burgdorferi
B) Rickettsia rickettsii
C) Anaplasma phagocytophilum
D) Ehrlichia chaffeensis

2. According to the current CDC-recommended laboratory algorithm for diagnosing HIV infection in adults and children aged >18 months, what is the recommended initial screening test?

A) HIV-1 p24 antigen assay only
B) HIV-1/HIV-2 antigen/antibody combination immunoassay
C) HIV RNA nucleic acid test (NAT)
D) HIV-1/HIV-2 antibody differentiation immunoassay

3. A patient presents with a pruritic rash consisting of raised, serpiginous tracks on their skin. The patient recently returned from a Caribbean vacation and reported walking barefoot on the beach. The MOST likely causative organism is:

A) Pediculus humanus
B) Larvae of Strongyloides stercoralis
C) Sarcoptes scabiei
D) Larvae of Ancylostoma braziliense

4. A patient with cystic fibrosis experiences a pulmonary exacerbation. Sputum culture grows a mucoid strain of Pseudomonas aeruginosa. The mucoid phenotype is primarily due to the overproduction of:

A) Alginate
B) Exotoxin A
C) Pyocyanin
D) Elastase

5. A 6-year-old child presents with a pharyngitis characterized by a grayish-white pseudomembrane covering the tonsils and posterior pharynx. Gram stain of the membrane reveals Gram-positive bacilli. Culture on Loeffler's medium shows growth of metachromatic granules. The MOST significant virulence factor associated with this organism's pathogenicity is:

A) Streptolysin O
B) Hyaluronidase
C) Protein A
D) Diphtheria toxin

Solutions: