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BPS Pharmacotherapy (Part1 and Part2) Sample Questions:

1. The results of a drug-use evaluation study by the P & T Committee reveal that 15 prescribers are using an antibiotic inappropriately. Which of the following is the most effective strategy for improving the drug therapy?

A) Sending the prescriber's a letter with the results of the study and educational material
B) Meeting in a seminar with the prescribers to review the results of the study
C) Including the results of the study and educational material in a newsletter distributed to the medical staff
D) Meeting individually with the prescribers to review the results of the study and review educational material

2. An 18-year-old patient presents with abrasions on the hands, knees, and shoulder from a recent bicycle accident. Gram-staining of surgical incision and drainage specimens reveals Gram positive cocci in chains. The patient has necrotizing fasciitis and develops bronchospasms after being given penicillin. Which intravenous antibiotic would be best to use in place of penicillin?

A) Ciprofloxacin
B) Clindamycin
C) Ceftriaxone
D) Sulfamethoxazole/trimethoprim

3. A patient with a COPD exacerbation is treated with prednisone 40 mg daily for one week with improvement. To discontinue the prednisone, the most appropriate procedure would be which of the following?

A) Reducing the daily prednisone dose by 50% every day until the patient is off the drug.
B) Stopping prednisone administration without dose tapering.
C) Reducing the daily prednisone dose by 50% every other day until it is down to 10 mg daily, then reducing it by 25% every other day until the patient is off the drug.
D) Reducing the daily prednisone dose by 25% every day until the patient is off the drug.

4. When low molecular weight heparin is prescribed, in which of the following patient populations would monitoring anti-factor-Xa levels be reasonable to consider?

A) Anticardiolipin antibody syndrome
B) Significant renal impairment
C) Protein C and Protein S deficiencies
D) Past history of GI bleeding

5. A 53-year-old patient with an 8-year history of diabetes is currently taking glipizide 10 mg twice daily before breakfast and supper. The patient weighs 85 kg and reports a 4.5 kg weight gain in the last year. Laboratory results are:
Creatinine: 1.2 mg/dL
A1C: 8.5%
What is the most appropriate recommendation at this time for improved diabetes control?

A) Continue with glipizide and add metformin.
B) Change glipizide to metformin.
C) Change glipizide to insulin.
D) Increase glipizide to 20 mg twice daily.

Solutions: