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American Society of Microbiology ABMM Exam Syllabus Topics:

American Society of Microbiology ABMM Sample Questions:

1. A patient with a history of chronic obstructive pulmonary disease (COPD) experiences an acute exacerbation.
Sputum culture grows numerous Gram-negative coccobacilli that are oxidase-positive and grow on chocolate agar but not on sheep blood agar. The MOST likely organism is:

A) Streptococcus pneumoniae
B) Moraxella catarrhalis
C) Haemophilus influenzae
D) Legionella pneumophila

2. A patient who received a solid organ transplant develops a pneumonia. Bronchoalveolar lavage fluid is positive for a single-stranded RNA virus that can cause giant cell formation with intranuclear and intracytoplasmic inclusions. The MOST likely causative agent is:

A) Adenovirus
B) Parainfluenza virus
C) Respiratory syncytial virus (RSV)
D) Human metapneumovirus

3. A clinical microbiology laboratory is using CRISPR-based technology for rapid and sensitive detection of specific bacterial DNA sequences directly from patient samples. This method relies on the ability of the Cas enzyme to:

A) Amplify target DNA sequences using specific primers and thermal cycling.
B) Specifically bind to and cleave target DNA sequences guided by a short RNA molecule.
C) Reverse transcribe RNA into complementary DNA.
D) Detect the presence of specific antibodies produced in response to bacterial infection.

4. A clinical microbiology laboratory is preparing a Gram stain of a mixed bacterial culture containing both Gram-positive and Gram-negative organisms. The correct order of reagents used in the Gram staining procedure is:

A) Iodine, crystal violet, decolorizer, safranin
B) Decolorizer, crystal violet, iodine, safranin
C) Crystal violet, iodine, decolorizer, safranin
D) Safranin, crystal violet, decolorizer, iodine

5. A child presents with a characteristic "slapped cheek" rash followed by a lacy, reticular rash on the trunk and extremities. The causative agent is a single-stranded DNA virus belonging to the family Parvoviridae, known as:

A) Rubella virus
B) Measles virus
C) Roseola virus (HHV-6)
D) Human parvovirus B19

Solutions: